JOINT-ON-CHIP
JOINT-ON-CHIP is a microengineered platform designed to replicate the
complex structure and function of a human joint in vitro. This system integrates
multiple tissue components, including synovial membrane, osteochondral
interface, and vascular networks, within a controlled microfluidic
environment and equipped with a mechanical actuator.
By mimicking the biochemical and mechanical interactions between these elements, the joint-on-chip enables the study of joint physiology and disease processes, such as inflammation and degeneration, in a highly realistic and dynamic way.
Potential applications
- Investigating the pathogenesis of joint diseases such as rheumatoid arthritis and osteoarthritis
- Screening and validating new anti-inflammatory or disease-modifying drugs
- Studying tissue-tissue crosstalk under physiological and pathological conditions
- Modeling patient-specific responses to enable precision medicine approaches
- Exploring mechanobiology through controlled mechanical stimuli that mimic joint loading and movement
JOINT-ON-CHIP
JOINT-ON-CHIP is a microengineered platform designed to replicate the
complex structure and function of a human joint in vitro. This system integrates
multiple tissue components, including synovial membrane, osteochondral
interface, and vascular networks, within a controlled microfluidic
environment and equipped with a mechanical actuator.
By mimicking the biochemical and mechanical interactions between these elements, the joint-on-chip enables the study of joint physiology and disease processes, such as inflammation and degeneration, in a highly realistic and dynamic way.
Potential applications
- Investigating the pathogenesis of joint diseases such as rheumatoid arthritis and osteoarthritis
- Screening and validating new anti-inflammatory or disease-modifying drugs
- Studying tissue-tissue crosstalk under physiological and pathological conditions
- Modeling patient-specific responses to enable precision medicine approaches
- Exploring mechanobiology through controlled mechanical stimuli that mimic joint loading and movement
Ai-Twin srl
Sede legale e operativa
C.so Trieste, 15/A – 28100 Novara (NO)
C.F./P.IVA 02722210032
SDI SUBM70N
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